Isopropanol → Isopropyl 4-bromobenzoate

Reaction equation

[Br:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[CH:4][CH:3]=1.[CH:11](O)([CH3:13])[CH3:12]>>[Br:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([O:8][CH:11]([CH3:13])[CH3:12])=[O:7])=[CH:4][CH:3]=1

Participants

Reactant 2

HCID 3776Isopropanol

HCID 114644-Bromobenzoic acid

Product 1

HCID 603913Isopropyl 4-bromobenzoateYield 97%

Procedure

Using General Esterification Procedure A; 4-bromobenzoic acid (1.50 g, 7.46 mmols) was combined with isopropyl alcohol to give 1.76 g (97%) of the title compound as a colorless oil.

Sources & evidence

ORD record: ord-8ad3e54d11904140885b84cf0ca77bf5
Source dataset: uspto-grants-2004_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06713647B2

Reaction notes

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