Hydrochloric Acid → Sodium Dilysine Succinate Hydrochloride

HRID 53072

Reaction equation

HRID 53072 reaction equation
O.[NH2:2][C@H:3]([C:9]([OH:11])=[O:10])[CH2:4][CH2:5][CH2:6][CH2:7][NH2:8].[C:12]([O-:19])(=[O:18])[CH2:13][CH2:14][C:15]([O-:17])=[O:16].[Na+:20].[Na+].C(O)(=O)CCC(O)=O.[ClH:30]>O>[ClH:30].[C:12]([O-:19])(=[O:18])[CH2:13][CH2:14][C:15]([O-:17])=[O:16].[NH2:2][C@H:3]([C:9]([OH:11])=[O:10])[CH2:4][CH2:5][CH2:6][CH2:7][NH2:8].[NH2:2][C@H:3]([C:9]([OH:11])=[O:10])[CH2:4][CH2:5][CH2:6][CH2:7][NH2:8].[Na+:20].[Na+:20]

Participants

6

Reactant 4

HCID 313Hydrochloric Acid2×HCID 1110Succinic AcidHCID 9020Sodium SuccinateHCID 16211825Lysine Monohydrate

Product 1

HCID 86749085Sodium Dilysine Succinate Hydrochloride

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

12 grams of L-lysine monohydrate is dissolved in 20 ml of water to which 6.0 ml of concentrated hydrochloric acid has been added. 2.964 grams of disodium succinate is added to neutralize some of the excess hydrochloric acid and 2.16 grams of succinic acid are added with mixing until effervescence ceases and all solids are dissolved. The solution is dried in a 110° C. oven until solids begin to form when cooled to room temperature. After 15 to 30 minutes solids form and are collected.

Workup

  1. additionhas been added
  2. additionare added
  3. additionwith mixing until effervescence ceases
  4. dissolutionall solids are dissolved
  5. customThe solution is dried in a 110° C. oven until solids
  6. customto form when
  7. customare collected

Sources & evidence

ORD record
ord-339483346657436b902a53b436f4e6f4
Source dataset
uspto-grants-1997_04
Patent number
US05618467

Linked notes

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