[N:1]([O-])=O.[Na+].[NH2:5][C:6]1[CH:14]=[CH:13][C:9]([C:10]([OH:12])=[O:11])=[C:8]([CH3:15])[C:7]=1[CH3:16].O.O.[Cl:19][Sn]Cl>O.Cl>[ClH:19].[CH3:15][C:8]1[C:7]([CH3:16])=[C:6]([NH:5][NH2:1])[CH:14]=[CH:13][C:9]=1[C:10]([OH:12])=[O:11]
A solution of 1.87 g of NaNO2 in 7 ml of water is added slowly to a solution, cooled to −5° C., of 4.5 g of 4-amino-2,3-dimethylbenzoic acid in 135 ml of concentrated HCl . After 2 hours of stirring at −5° C., a solution of 25 g of SnCl2.2H2O in 250 ml of concentrated HCl is added at −10° C., and the mixture is stirred for 30 minutes at −5° C. and then 2 hours at RT. The mixture is filtered, and the precipitate is washed with 5 ml of concentrated HCl and dried under a stream of dry nitrogen and then under vacuum to obtain 5.5 g of expected product.
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