Hydrochloric Acid → HCID 19600253, compound
Reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][C:13]([N:15]2[CH2:20][CH2:19][C:18]3[CH:21]=[C:22]([CH2:24][N:25]([CH3:27])[CH3:26])[O:23][C:17]=3[CH2:16]2)=[O:14])=[CH:4][CH:3]=1.Cl>CO.C(OCC)(=O)C>[ClH:1].[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][C:13]([N:15]2[CH2:20][CH2:19][C:18]3[CH:21]=[C:22]([CH2:24][N:25]([CH3:27])[CH3:26])[O:23][C:17]=3[CH2:16]2)=[O:14])=[CH:4][CH:3]=1Participants
5
Reactant 2
Product 1
Reagents, catalysts & solvents 2
Procedure
6-(4-Chlorophenyl)-1-(2-dimethylaminomethyl-5,7-dihydro-4H-furo[2,3-c]pyridin-6-yl)hexan-1-one 0.528 g was dissolved in 2 ml of methanol; hydrogen chloride in ethyl acetate was added in excess, followed by stirring. This solution was concentrated and washed with diethyl ether to yield the desired product.