5-Chloro-2-nitrobenzoic acid → 5-Chloro-2-nitrobenzoyl chloride

HRID 654459

Reaction equation

[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([N+:11]([O-:13])=[O:12])=[C:6]([CH:10]=1)[C:7](O)=[O:8].S(Cl)([Cl:16])=O>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([N+:11]([O-:13])=[O:12])=[C:6]([CH:10]=1)[C:7]([Cl:16])=[O:8]

Participants

Reactant 2

HCID 172865-Chloro-2-nitrobenzoic acid

HCID 24386Thionyl Chloride

Product 1

HCID 27236855-Chloro-2-nitrobenzoyl chloride

Conditions

Temperature: 90 °C

Procedure

A mixture of 80.6 g of 5-chloro-2-nitrobenzoic acid and 58.2 ml of thionyl chloride is heated at 90° C. for 2 hours. The excess thionyl chloride is then distilled off in vacuo. 87.1 g of 5-chloro-2-nitrobenzoyl chloride are obtained.

Workup

distillationThe excess thionyl chloride is then distilled off in vacuo

Sources & evidence

ORD record: ord-a77377dc679e46d883508eddd15de74a
Source dataset: uspto-grants-1992_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05132314

Linked notes

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