Chloride → N-[4-(1-diphenylphosphinyl-piperidin-4-yl)-butyl]-3-(pyridin-3-yl)-propionamide

HRID 662910

Reaction equation

HRID 662910 reaction equation
[CH2:38]1[O:39][CH2:40][CH2:41][CH2:42]1.[Cl-:1].[NH:17]1[CH2:18][CH2:19][CH:20]([CH2:23][CH2:24][CH2:25][CH2:26][NH:27][C:28]([CH2:29][CH2:30][c:31]2[cH:32][n:33][cH:34][cH:35][cH:36]2)=[O:37])[CH2:21][CH2:22]1.[c:2]1([P:8]([OH:9])(=[O:10])[c:11]2[cH:12][cH:13][cH:14][cH:15][cH:16]2)[cH:3][cH:4][cH:5][cH:6][cH:7]1>>[c:2]1([P:8](=[O:10])([c:11]2[cH:12][cH:13][cH:14][cH:15][cH:16]2)[N:17]2[CH2:18][CH2:19][CH:20]([CH2:23][CH2:24][CH2:25][CH2:26][NH:27][C:28]([CH2:29][CH2:30][c:31]3[cH:32][n:33][cH:34][cH:35][cH:36]3)=[O:37])[CH2:21][CH2:22]2)[cH:3][cH:4][cH:5][cH:6][cH:7]1

Participants

5

Reactant 4

HCID 312ChlorideHCID 8028TetrahydrofuranHCID 15567Diphenylphosphinic acidHCID 18425707N-(4-piperidin-4-yl-butyl)-3-(pyridin-3-yl)-propionamide

Product 1

HCID 18431541N-[4-(1-diphenylphosphinyl-piperidin-4-yl)-butyl]-3-(pyridin-3-yl)-propionamide

Sources & evidence

ORD record
ord-ac8b8b938f0e4ce68aac4dd04470be52
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Linked notes

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