Hydrochloric Acid → Tert-butyl 4-(4-chloro-1,2,5-thiadiazol-3-yl)piperazine-1-carboxylate

HRID 665071

Reaction equation

HRID 665071 reaction equation
[C:1](=[O:2])([O:3][C:4]([CH3:5])([CH3:6])[CH3:7])[N:8]1[CH2:9][CH2:10][NH:11][CH2:12][CH2:13]1.[Cl:14][c:15]1[n:16][s:17][n:18][c:19]1[Cl:20].[ClH:21].[O:22]=[CH:23][N:24]([CH3:25])[CH3:26].[OH2:27]>>[C:1](=[O:2])([O:3][C:4]([CH3:5])([CH3:6])[CH3:7])[N:8]1[CH2:9][CH2:10][N:11]([c:19]2[c:15]([Cl:14])[n:16][s:17][n:18]2)[CH2:12][CH2:13]1

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 962WaterHCID 6228DimethylformamideHCID 798043,4-Dichloro-1,2,5-thiadiazoleHCID 143452tert-Butyl piperazine-1-carboxylate

Product 1

HCID 15524001Tert-butyl 4-(4-chloro-1,2,5-thiadiazol-3-yl)piperazine-1-carboxylate

Sources & evidence

ORD record
ord-d05992d773744bfb818cbe1b1857002a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Linked notes

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