Tetrahydrofuran → 3-[4-(1-benzyl-3,6-dihydro-2H-pyridin-4-yl)-3-fluorophenyl]-5-(1,2-oxazol-3-yloxymethyl)-1,3-oxazolidin-2-one

HRID 669779

Reaction equation

HRID 669779 reaction equation
[O:54]1[CH2:55][CH2:56][CH2:57][CH2:58]1.[OH:1][CH2:2][CH:3]1[CH2:4][N:5]([c:9]2[cH:10][c:11]([F:28])[c:12]([C:15]3=[CH:16][CH2:17][N:18]([CH2:21][c:22]4[cH:23][cH:24][cH:25][cH:26][cH:27]4)[CH2:19][CH2:20]3)[cH:13][cH:14]2)[C:6](=[O:8])[O:7]1.[OH:29][c:30]1[n:31][o:32][cH:33][cH:34]1.[c:35]1([P:36]([c:37]2[cH:38][cH:39][cH:40][cH:41][cH:42]2)[c:43]2[cH:44][cH:45][cH:46][cH:47][cH:48]2)[cH:49][cH:50][cH:51][cH:52][cH:53]1>>[O:1]([CH2:2][CH:3]1[CH2:4][N:5]([c:9]2[cH:10][c:11]([F:28])[c:12]([C:15]3=[CH:16][CH2:17][N:18]([CH2:21][c:22]4[cH:23][cH:24][cH:25][cH:26][cH:27]4)[CH2:19][CH2:20]3)[cH:13][cH:14]2)[C:6](=[O:8])[O:7]1)[c:30]1[n:31][o:32][cH:33][cH:34]1

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 11776TriphenylphosphineHCID 218765573-[4-(1-benzyl-3,6-dihydro-2H-pyridin-4-yl)-3-fluorophenyl]-5-(hydroxymethyl)-1,3-oxazolidin-2-oneHCID 178516613HCID 178516613, compound

Product 1

HCID 229960823-[4-(1-benzyl-3,6-dihydro-2H-pyridin-4-yl)-3-fluorophenyl]-5-(1,2-oxazol-3-yloxymethyl)-1,3-oxazolidin-2-one

Sources & evidence

ORD record
ord-78310732393c4641bb57b4d3cb0be6d2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Linked notes

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