2-Methyltetrahydrofuran → 3-(3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazine-2-carbonyl)-N-(2,6-difluorophenyl)benzenesulfonamide

HRID 673814

Reaction equation

HRID 673814 reaction equation
[CH2:22]1[CH:23]2[N:24]([CH2:25][CH2:26][NH:27]1)[CH2:28][CH2:29][CH2:30]2.[CH3:31][N:32]([CH3:33])[C:34](=[O:35])[CH3:36].[CH3:37][CH:38]1[CH2:39][CH2:40][CH2:41][O:42]1.[F:1][c:2]1[c:3]([NH:9][S:10](=[O:11])(=[O:12])[c:13]2[cH:14][c:15]([C:16](=[O:17])[OH:18])[cH:19][cH:20][cH:21]2)[c:4]([F:8])[cH:5][cH:6][cH:7]1>>[F:1][c:2]1[c:3]([NH:9][S:10](=[O:11])(=[O:12])[c:13]2[cH:14][c:15]([C:16](=[O:18])[N:27]3[CH2:22][CH:23]4[N:24]([CH2:25][CH2:26]3)[CH2:28][CH2:29][CH2:30]4)[cH:19][cH:20][cH:21]2)[c:4]([F:8])[cH:5][cH:6][cH:7]1

Participants

5

Reactant 4

HCID 73012-MethyltetrahydrofuranHCID 31374DimethylacetamideHCID 558578Octahydropyrrolo(1,2-a)pyrazineHCID 244221893-{[(2,6-Difluorophenyl)amino]sulfonyl}benzoic acid

Product 1

HCID 752323823-(3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazine-2-carbonyl)-N-(2,6-difluorophenyl)benzenesulfonamide

Sources & evidence

ORD record
ord-8a801439327243b59c73b7f337bfe9e5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Linked notes

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