Hydroxide → 5-Ethylpyrazin-2-amine

Reaction equation

[C:1](#[CH:2])[c:3]1[n:4][cH:5][c:6]([NH2:9])[n:7][cH:8]1.[CH3:10][CH2:11][N:12]([CH2:13][CH3:14])[CH2:15][CH3:16].[CH3:17][CH2:18][O:19][C:20](=[O:21])[CH3:22].[OH-:23].[OH-:24].[Pd+2:25]>>[CH2:1]([CH3:2])[c:3]1[n:4][cH:5][c:6]([NH2:9])[n:7][cH:8]1

Participants

Reactant 5

HCID 961Hydroxide2×

HCID 8471Triethylamine

HCID 8857Ethyl Acetate

HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)

HCID 22046532HCID 22046532, compound

Product 1

HCID 220463235-Ethylpyrazin-2-amine

Sources & evidence

ORD record: ord-94b363e655ae467dabf6752089b6860f
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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