Tetrahydrofuran → (2-Benzylisoindolin-5-yl)methanol

HRID 680075

Reaction equation

HRID 680075 reaction equation
[Al+3:22].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][c:10]2[cH:11][cH:12][c:13]([C:17](=[O:18])[O:19][CH3:20])[cH:14][c:15]2[CH2:16]1.[H-:21].[H-:24].[H-:25].[H-:26].[Li+:23].[O:27]1[CH2:28][CH2:29][CH2:30][CH2:31]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][c:10]2[cH:11][cH:12][c:13]([CH2:17][OH:18])[cH:14][c:15]2[CH2:16]1

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 104727Aluminum CationHCID 166653Hydride4×HCID 23301778Methyl 2-benzylisoindoline-5-carboxylate

Product 1

HCID 19828502(2-Benzylisoindolin-5-yl)methanol

Sources & evidence

ORD record
ord-b03477c76ae14f57939b1ae535888cf5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Linked notes

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