Hydroxide → 1-Benzyl-4-hydroxy-1,3-dihydro-benzoimidazol-2-one

Reaction equation

[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[n:8]1[c:9](=[O:25])[nH:10][c:11]2[c:12]1[cH:13][cH:14][cH:15][c:16]2[O:17][CH2:18][c:19]1[cH:20][cH:21][cH:22][cH:23][cH:24]1.[CH2:26]1[O:27][CH2:28][CH2:29][CH2:30]1.[CH3:31][CH2:32][O:33][C:34](=[O:35])[CH3:36].[OH-:37].[OH-:39].[Pd+2:38]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[n:8]1[c:9](=[O:25])[nH:10][c:11]2[c:12]1[cH:13][cH:14][cH:15][c:16]2[OH:17]

Participants

Reactant 5

HCID 961Hydroxide2×

HCID 8028Tetrahydrofuran

HCID 8857Ethyl Acetate

HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)

HCID 578350031-Benzyl-4-benzyloxy-1,3-dihydro-benzoimidazol-2-one

Product 1

HCID 578349841-Benzyl-4-hydroxy-1,3-dihydro-benzoimidazol-2-one

Sources & evidence

ORD record: ord-471fcd0c15854745a8471823d6605f6d
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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