Methane → 3-[2,6-Dimethoxy-4-(methoxymethyl)phenyl]-6-methoxypyrazolo[5,1-b][1,3]thiazole-7-amine

Reaction equation

[C:26].[CH3:1][O:2][c:3]1[c:4](-[c:14]2[n:15]3[c:16]([s:17][cH:18]2)[c:19]([N:24]=[O:25])[c:20]([O:22][CH3:23])[n:21]3)[c:5]([O:12][CH3:13])[cH:6][c:7]([CH2:9][O:10][CH3:11])[cH:8]1.[CH3:28][CH2:29][O:30][C:31](=[O:32])[CH3:33].[Pd:27]>>[CH3:1][O:2][c:3]1[c:4](-[c:14]2[n:15]3[c:16]([s:17][cH:18]2)[c:19]([NH2:24])[c:20]([O:22][CH3:23])[n:21]3)[c:5]([O:12][CH3:13])[cH:6][c:7]([CH2:9][O:10][CH3:11])[cH:8]1

Participants

Reactant 4

HCID 297Methane

HCID 8857Ethyl Acetate

HCID 23938Palladium

HCID 57912454HCID 57912454, compound

Product 1

HCID 579124433-[2,6-Dimethoxy-4-(methoxymethyl)phenyl]-6-methoxypyrazolo[5,1-b][1,3]thiazole-7-amine

Sources & evidence

ORD record: ord-eb81f72a4e4b4ba48468fcf0106bbc46
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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