Dimethylformamide → 2-(2,2-difluoroethyl)-1H-isoindole-1,3(2H)-dione
Reaction equation
[C:6]1(=[O:16])[c:7]2[c:8]([cH:12][cH:13][cH:14][cH:15]2)[C:9](=[O:11])[NH:10]1.[CH3:18][N:19]([CH3:20])[CH:21]=[O:22].[F:1][CH:2]([CH2:3][Cl:4])[F:5].[K:17]>>[F:1][CH:2]([CH2:3][N:10]1[C:6](=[O:16])[c:7]2[c:8]([cH:12][cH:13][cH:14][cH:15]2)[C:9]1=[O:11])[F:5]Participants
5
Sources & evidence
- ORD record
- ord-fb2a88655b084c75b4fc74ce18aada1b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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