Tetrahydrofuran → 4-Benzyl-1-[2-(2-fluorophenyl)propyl]piperazine
Reaction equation
[Al+3:2].[CH2:31]1[O:32][CH2:33][CH2:34][CH2:35]1.[CH2:7]([c:8]1[cH:9][cH:10][cH:11][cH:12][cH:13]1)[N:14]1[CH2:15][CH2:16][N:17]([C:20]([CH:21]([CH3:22])[c:23]2[c:24]([F:29])[cH:25][cH:26][cH:27][cH:28]2)=[O:30])[CH2:18][CH2:19]1.[H-:1].[H-:4].[H-:5].[H-:6].[Li+:3]>>[CH2:7]([c:8]1[cH:9][cH:10][cH:11][cH:12][cH:13]1)[N:14]1[CH2:15][CH2:16][N:17]([CH2:20][CH:21]([CH3:22])[c:23]2[c:24]([F:29])[cH:25][cH:26][cH:27][cH:28]2)[CH2:18][CH2:19]1Participants
6
Sources & evidence
- ORD record
- ord-21d8221c8404477d98aa343a6524c5e4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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