Ammonium → Tert-butyl 3-bromo-5-(2,2-difluoro-1-hydroxyethyl)benzoate
Reaction equation
[Br:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[O:7][C:8]([CH3:9])([CH3:10])[CH3:11])[cH:12][c:13]([Br:15])[cH:14]1.[CH3:24][OH:25].[Cl-:26].[F:16][CH:17]([C:18](=[O:19])[O:20][CH2:21][CH3:22])[F:23].[NH4+:27].[O:28]1[CH2:29][CH2:30][CH2:31][CH2:32]1>>[c:2]1([CH:18]([CH:17]([F:16])[F:23])[OH:19])[cH:3][c:4]([C:5](=[O:6])[O:7][C:8]([CH3:9])([CH3:10])[CH3:11])[cH:12][c:13]([Br:15])[cH:14]1Participants
7
Sources & evidence
- ORD record
- ord-bd5a912184c14f099c2ef957f9e52c19
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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