Dimethylformamide → Phenylmethyl [4-[[[5-(dimethylamino)-1-naphthalenyl]sulfonyl]amino]-5-[4-ethyl-1-piperidinyl]-5-oxopentyl]carbamate

HRID 697653

Reaction equation

HRID 697653 reaction equation
[CH2:43]([CH3:44])[CH:45]1[CH2:46][CH2:47][NH:48][CH2:49][CH2:50]1.[CH3:1][N:2]([c:3]1[c:4]2[cH:5][cH:6][cH:7][c:8]([S:13](=[O:14])(=[O:15])[NH:16][CH:17]([C:18](=[O:19])[OH:20])[CH2:21][CH2:22][CH2:23][NH:24][C:25](=[O:26])[O:27][CH2:28][c:29]3[cH:30][cH:31][cH:32][cH:33][cH:34]3)[c:9]2[cH:10][cH:11][cH:12]1)[CH3:35].[CH3:36][CH2:37][N:38]([CH2:39][CH3:40])[CH2:41][CH3:42].[CH3:68][N:69]([CH3:70])[CH:71]=[O:72].[c:51]1([P:52]([N:53]=[N+:54]=[N-:55])([c:56]2[cH:57][cH:58][cH:59][cH:60][cH:61]2)=[O:62])[cH:63][cH:64][cH:65][cH:66][cH:67]1>>[CH3:1][N:2]([c:3]1[c:4]2[cH:5][cH:6][cH:7][c:8]([S:13](=[O:14])(=[O:15])[NH:16][CH:17]([C:18](=[O:19])[N:48]3[CH2:47][CH2:46][CH:45]([CH2:43][CH3:44])[CH2:50][CH2:49]3)[CH2:21][CH2:22][CH2:23][NH:24][C:25](=[O:26])[O:27][CH2:28][c:29]3[cH:30][cH:31][cH:32][cH:33][cH:34]3)[c:9]2[cH:10][cH:11][cH:12]1)[CH3:35]

Participants

6

Reactant 5

HCID 6228DimethylformamideHCID 8471TriethylamineHCID 767044-EthylpiperidineHCID 199401P,P-Diphenylphosphinic azideHCID 197931492-[[[5-(Dimethylamino)-1-naphthalenyl]sulfonyl]amino]-5-[[(phenylmethoxy)carbonyl]amino]pentanoic acid

Product 1

HCID 54192395Phenylmethyl [4-[[[5-(dimethylamino)-1-naphthalenyl]sulfonyl]amino]-5-[4-ethyl-1-piperidinyl]-5-oxopentyl]carbamate

Sources & evidence

ORD record
ord-97652281fc104e1286dbbfb15872d8f9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Linked notes

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