Hydrochloric Acid → 3,3,3-trifluoro-N-(4-{[3-(4-methoxybenzyl)-2-oxo-1,2,3,4-tetrahydropyrido[2,3-d]pyrimidin-5-yl]amino}phenyl)propanamide

HRID 699404

Reaction equation

HRID 699404 reaction equation
[CH3:38][N:39]1[CH2:40][CH2:41][CH2:42][C:43]1=[O:44].[Cl:1][c:2]1[cH:3][cH:4][n:5][c:6]2[c:11]1[CH2:10][N:9]([CH2:12][c:13]1[cH:14][cH:15][c:16]([O:19][CH3:20])[cH:17][cH:18]1)[C:8](=[O:21])[NH:7]2.[ClH:37].[NH2:22][c:23]1[cH:24][cH:25][c:26]([NH:29][C:30]([CH2:31][C:32]([F:33])([F:34])[F:35])=[O:36])[cH:27][cH:28]1>>[c:2]1([NH:22][c:23]2[cH:24][cH:25][c:26]([NH:29][C:30]([CH2:31][C:32]([F:33])([F:34])[F:35])=[O:36])[cH:27][cH:28]2)[cH:3][cH:4][n:5][c:6]2[c:11]1[CH2:10][N:9]([CH2:12][c:13]1[cH:14][cH:15][c:16]([O:19][CH3:20])[cH:17][cH:18]1)[C:8](=[O:21])[NH:7]2

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 13387N-methyl-2-pyrrolidoneHCID 16772763N-(4-Aminophenyl)-3,3,3-trifluoropropanamideHCID 669262915-chloro-3-[(4-methoxyphenyl)methyl]-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-2-one

Product 1

HCID 704976753,3,3-trifluoro-N-(4-{[3-(4-methoxybenzyl)-2-oxo-1,2,3,4-tetrahydropyrido[2,3-d]pyrimidin-5-yl]amino}phenyl)propanamide

Sources & evidence

ORD record
ord-a6e0b646814941999096d0c3d2680f0d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Linked notes

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