Tetrahydrofuran → 3-(Phenylethynyl)-1-benzofuran-5-carbaldehyde

Reaction equation

[Br:1][c:2]1[cH:3][o:4][c:5]2[c:6]1[cH:7][c:8]([CH:11]=[O:12])[cH:9][cH:10]2.[CH2:21]1[O:22][CH2:23][CH2:24][CH2:25]1.[Cu:26][I:27].[c:13]1([C:19]#[CH:20])[cH:14][cH:15][cH:16][cH:17][cH:18]1>>[c:2]1([C:20]#[C:19][c:13]2[cH:14][cH:15][cH:16][cH:17][cH:18]2)[cH:3][o:4][c:5]2[c:6]1[cH:7][c:8]([CH:11]=[O:12])[cH:9][cH:10]2

Participants

Reactant 4

HCID 8028Tetrahydrofuran

HCID 10821Phenylacetylene

HCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)

HCID 574696633-Bromo-benzofuran-5-carbaldehyde

Product 1

HCID 574696653-(Phenylethynyl)-1-benzofuran-5-carbaldehyde

Sources & evidence

ORD record: ord-2b9b5e573f08418e9f917c8bad2bd3e1
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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