Hydrochloric Acid → HCID 53758232, compound
Reaction equation
[C:1]([NH:4][C:5]([C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)=[C:6]([CH3:12])[C:7]([O:9]CC)=[O:8])(=[O:3])[CH3:2].[OH-].[Na+].O.Cl>C(O)(C)C>[C:1]([NH:4][C:5]([C:13]1[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=1)=[C:6]([CH3:12])[C:7]([OH:9])=[O:8])(=[O:3])[CH3:2]Participants
6
Reactant 4
Product 1
Reagents, catalysts & solvents 1
Procedure
80 g of the product of Step A were stirred for 5 hours in 400 ml of isopropanol and 48.5 ml of sodium hydroxide and the solution was poured into a liter of water taken to pH 1 with concentrated hydrochloric acid. The precipitate was separated, washed with water and dried under reduced pressure to obtain 42 g of the expected product melting at 190° C.
Workup
- customThe precipitate was separated
- washwashed with water
- customdried under reduced pressure
Sources & evidence
- ORD record
- ord-458bd8b4ca3b4dbabeedbb0f3d4785cb
- Source dataset
- uspto-grants-1991_01
- Patent number
- US04987140
Reaction notes
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