Hexane → Chloramben-methyl

HRID 705455

Reaction equation

HRID 705455 reaction equation
[Cl:1][C:2]1[C:10]([NH2:11])=[CH:9][C:8]([Cl:12])=[CH:7][C:3]=1[C:4]([OH:6])=[O:5].[CH3:13]CCCCC.C[Si](C=[N+]=[N-])(C)C>CC(C)=O>[Cl:1][C:2]1[C:10]([NH2:11])=[CH:9][C:8]([Cl:12])=[CH:7][C:3]=1[C:4]([O:6][CH3:13])=[O:5]

Participants

5

Reactant 3

HCID 8058HexaneHCID 8630ChlorambenHCID 167693Trimethylsilyldiazomethane

Product 1

HCID 23714Chloramben-methyl

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

206 mg (1.0 mmol) of 2,5-Dichloro-3-aminobenzoic acid was dissolved in 4 mL of acetone. 0.7 mL (1.4 mmol) of A hexane solution of 2.0M trimethylsilyldiazomethane was added thereto and stirred at room temperature for 1.5 hours. A solvent was removed to obtain methyl 2,5-dichloro-3-aminobenzoate.

Workup

  1. customA solvent was removed

Sources & evidence

ORD record
ord-1cfcecd5fdcd4c12abcdfff6406355ba
Source dataset
uspto-grants-2015_11
Patent number
US09174932B2

Linked notes

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