Formamide → (5R)-5-{(E)-2-(4-tert-butylphenyl)-2-[5-(dimethylamino)-6-methoxypyridin-2-yl]ethenyl}pyrrolidin-2-one

Reaction equation

[CH:1]([NH2:3])=O.N[C:5]1[CH:6]=[CH:7][C:8](/[C:13](/[C:21]2[CH:26]=[CH:25][C:24]([C:27]([CH3:30])([CH3:29])[CH3:28])=[CH:23][CH:22]=2)=[CH:14]/[C@@H:15]2[NH:19]C(=O)C[CH2:16]2)=[N:9][C:10]=1OC.C(O[BH-](O[C:41](=[O:43])[CH3:42])OC(=O)C)(=O)C.[Na+].[C:45](=[O:48])(O)[O-].[Na+].[C:50](#N)C>>[C:27]([C:24]1[CH:25]=[CH:26][C:21](/[C:13](/[C:8]2[CH:7]=[CH:6][C:5]([N:3]([CH3:1])[CH3:50])=[C:10]([O:48][CH3:45])[N:9]=2)=[CH:14]\[C@@H:15]2[NH:19][C:41](=[O:43])[CH2:42][CH2:16]2)=[CH:22][CH:23]=1)([CH3:28])([CH3:29])[CH3:30]