p-Toluenesulfonic acid → HCID 11807640, compound

HRID 724831

Reaction equation

HRID 724831 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([CH2:10][C:11]([O-:13])=[O:12])=[CH:6][CH:5]=1)([O-:3])=[O:2].[C:14]1(C)C=CC(S(O)(=O)=O)=C[CH:15]=1.F[C:26](F)(F)[C:27]([OH:29])=[O:28]>C1C=CC=CC=1>[CH2:14]([O:12][C:11]([CH:10]([C:7]1[CH:6]=[CH:5][C:4]([N+:1]([O-:3])=[O:2])=[CH:9][CH:8]=1)[CH2:26][C:27]([OH:29])=[O:28])=[O:13])[CH3:15]

Participants

5

Reactant 3

HCID 6101p-Toluenesulfonic acidHCID 6422Trifluoroacetic acidHCID 6931101(4-Nitrophenyl)acetate

Product 1

HCID 11807640HCID 11807640, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

Following a similar procedure to that described in reference example 7b, but starting fromethyl 4-nitrophenylacetate instead of ethyl diphenylacetate, and hydrolizing then the tert-butyl ester using p-toluenesulfonic acid in benzene at reflux instead of using trifluoroacetic acid, the title compound was obtained.

Sources & evidence

ORD record
ord-c2c552ccf12b44bfa6feed885d81df99
Source dataset
uspto-grants-1998_01
Patent number
US05705504

Linked notes

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