Catechol → Adamantane

HRID 73722

Reaction equation

HRID 73722 reaction equation
C1(C(=CC=CC=1)O)O.[C:9]12(O)[CH2:18][CH:13]3[CH2:14][CH:15]([CH2:17][C:11](O)([CH2:12]3)[CH2:10]1)[CH2:16]2>>[CH:9]12[CH2:18][CH:13]3[CH2:14][CH:15]([CH2:17][CH:11]([CH2:12]3)[CH2:10]1)[CH2:16]2

Participants

3

Reactant 2

HCID 289CatecholHCID 5738291,3-Adamantanediol

Product 1

HCID 9238Adamantane

Procedure

Reaction of catechol with 1,3-adamantane-diol according to the method described by Lu et al (Lu et al. J Med Chem 2005, 48 (14), 4576-4585) gave the adduct 10 in reasonable yield.

Sources & evidence

ORD record
ord-9d3c66bda5c744139c0dfc7fe0fcf80f
Source dataset
uspto-grants-2014_09
Patent number
US08829198B2

Linked notes

Loading…