Hydrochloric Acid → Benzoic acid, 2-(aminosulfonyl)-, methyl ester

HRID 745889

Reaction equation

HRID 745889 reaction equation
Cl.[S:2]1([C:13]2[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=2)[C:6](=[O:7])[NH:5]1)(=[O:4])=[O:3].[CH3:14][OH:15]>>[CH3:14][O:15][C:6](=[O:7])[C:8]1[CH:9]=[CH:10][CH:11]=[CH:12][C:13]=1[S:2](=[O:4])(=[O:3])[NH2:5]

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 887MethanolHCID 5143Saccharin

Product 1

HCID 42546Benzoic acid, 2-(aminosulfonyl)-, methyl ester

Procedure

An HCl stream is led under cooling into a suspension of 143.3 g (0.78 mol) in 600 ml absolute methanol until saturation. Subsequently the solution is refluxed yet two hours until the saccharine has gone completely into solution and the reaction has terminated.

Workup

  1. customthe reaction has terminated

Sources & evidence

ORD record
ord-7682b66929384626b8eedbdba4fb52da
Source dataset
uspto-grants-1986_07
Patent number
US04601746

Linked notes

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