Diisopropylamine → Thiazole-5-carboxylic acid (2-(4-(2-cyclobutoxy-pyrimidin-5-ylethynyl)-phenyl)-1-methyl-ethyl)-amide
Reaction equation
I[C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH:9]([NH:11][C:12]([C:14]2[S:18][CH:17]=[N:16][CH:15]=2)=[O:13])[CH3:10])=[CH:4][CH:3]=1.C(NC(C)C)(C)C.[CH:26]1([O:30][C:31]2[N:36]=[CH:35][C:34]([C:37]#[CH:38])=[CH:33][N:32]=2)[CH2:29][CH2:28][CH2:27]1>Cl[Pd](Cl)([P](C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1)[P](C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1.[Cu]I.C1COCC1>[CH:26]1([O:30][C:31]2[N:32]=[CH:33][C:34]([C:37]#[C:38][C:2]3[CH:7]=[CH:6][C:5]([CH2:8][CH:9]([NH:11][C:12]([C:14]4[S:18][CH:17]=[N:16][CH:15]=4)=[O:13])[CH3:10])=[CH:4][CH:3]=3)=[CH:35][N:36]=2)[CH2:27][CH2:28][CH2:29]1Participants
7
