Dimethylformamide → 1-(9H-carbazol-4-yloxy)-3-{[1-(5-nitro-2-furoyl)piperidin-4-yl]amino}propan-2-ol

HRID 802098

Reaction equation

HRID 802098 reaction equation
[CH3:12][CH2:13][N:14]=[C:15]=[N:16][CH2:17][CH2:18][CH2:19][N:20]([CH3:21])[CH3:22].[Cl:63][CH2:64][Cl:65].[N+:1](=[O:2])([O-:3])[c:4]1[cH:5][cH:6][c:7]([C:9](=[O:10])[OH:11])[o:8]1.[O:58]=[CH:59][N:60]([CH3:61])[CH3:62].[OH:23][n:24]1[c:25]2[c:26]([cH:27][cH:28][cH:29][cH:30]2)[n:31][n:32]1.[cH:33]1[cH:34][cH:35][c:36]([O:46][CH2:47][CH:48]([CH2:49][NH:50][CH:51]2[CH2:52][CH2:53][NH:54][CH2:55][CH2:56]2)[OH:57])[c:37]2[c:38]3[cH:39][cH:40][cH:41][cH:42][c:43]3[nH:44][c:45]12>>[N+:1](=[O:2])([O-:3])[c:4]1[cH:5][cH:6][c:7]([C:9](=[O:11])[N:54]2[CH2:53][CH2:52][CH:51]([NH:50][CH2:49][CH:48]([CH2:47][O:46][c:36]3[cH:35][cH:34][cH:33][c:45]4[c:37]3[c:38]3[cH:39][cH:40][cH:41][cH:42][c:43]3[nH:44]4)[OH:57])[CH2:56][CH2:55]2)[o:8]1

Participants

7

Reactant 6

HCID 6228DimethylformamideHCID 6344DichloromethaneHCID 125775-Nitro-2-Furoic AcidHCID 159081-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 757711-HydroxybenzotriazoleHCID 588781181-(9H-carbazol-4-yloxy)-3-(piperidin-4-ylamino)propan-2-ol

Product 1

HCID 167312171-(9H-carbazol-4-yloxy)-3-{[1-(5-nitro-2-furoyl)piperidin-4-yl]amino}propan-2-ol

Sources & evidence

ORD record
ord-a978add2f0454aa38281896d65dfc6c5
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Linked notes

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