Hydrochloric Acid → 4-bromo-2,3-dihydro-1H-isoindole
Reaction equation
[CH2:2]([c:3]1[cH:4][cH:5][cH:6][cH:7][cH:8]1)[N:9]1[CH2:10][c:11]2[cH:12][cH:13][cH:14][c:15]([Br:18])[c:16]2[CH2:17]1.[CH3:28][CH2:29][O:30][C:31]([CH3:32])=[O:33].[Cl:21][CH:22]([O:23][C:24]([Cl:25])=[O:26])[CH3:27].[ClH:1].[Na+:20].[OH-:19]>>[NH:9]1[CH2:10][c:11]2[cH:12][cH:13][cH:14][c:15]([Br:18])[c:16]2[CH2:17]1Participants
7
Sources & evidence
- ORD record
- ord-e6da086ad0d44efb9d4f5c363402fd11
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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