Hydrochloric Acid → 1-Benzyl 3-methyl 4-oxopiperidine-1,3-dicarboxylate

HRID 812152

Reaction equation

HRID 812152 reaction equation
[C:1]([N:2]1[CH2:3][CH2:4][CH2:5][CH:6]([C:7]([O:8][CH2:9][CH3:10])=[O:11])[CH2:12]1)(=[O:13])[c:14]1[cH:15][cH:16][cH:17][cH:18][cH:19]1.[Cl:32][C:33](=[O:34])[O:35][CH2:36][c:37]1[cH:38][cH:39][cH:40][cH:41][cH:42]1.[ClH:20].[O:21]=[C:22]1[CH:23]([C:28](=[O:29])[O:30][CH3:31])[CH2:24][NH:25][CH2:26][CH2:27]1>>[O:21]=[C:22]1[CH:23]([C:28](=[O:29])[O:30][CH3:31])[CH2:24][N:25]([C:33](=[O:34])[O:35][CH2:36][c:37]2[cH:38][cH:39][cH:40][cH:41][cH:42]2)[CH2:26][CH2:27]1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 10387Benzyl chloroformateHCID 2724029Methyl 4-oxopiperidine-3-carboxylateHCID 3784394Ethyl 1-benzoyl-3-piperidinecarboxylate

Product 1

HCID 157481361-Benzyl 3-methyl 4-oxopiperidine-1,3-dicarboxylate

Sources & evidence

ORD record
ord-1cddf8a0a1a64628b23dad029cd69eb8
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Linked notes

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