Tetrahydrofuran → 1-(3-(6,7-dimethoxyquinazolin-4-yloxy)phenyl)-3-(3-isopropyl-1-(pyridin-3-yl)-1H-pyrazol-5-yl)urea

Reaction equation

[CH2:47]1[O:48][CH2:49][CH2:50][CH2:51]1.[CH3:1][O:2][c:3]1[cH:4][c:5]2[c:6]([O:15][c:16]3[cH:17][c:18]([NH2:19])[cH:20][cH:21][cH:22]3)[n:7][cH:8][n:9][c:10]2[cH:11][c:12]1[O:13][CH3:14].[CH3:52][N:53]([c:54]1[cH:55][cH:56][n:57][cH:58][cH:59]1)[CH3:60].[CH:23]([CH3:24])([CH3:25])[c:26]1[n:27][n:28](-[c:41]2[cH:42][n:43][cH:44][cH:45][cH:46]2)[c:29]([NH:31][C:32]([O:33][c:35]2[cH:36][cH:37][cH:38][cH:39][cH:40]2)=[O:34])[cH:30]1>>[CH3:1][O:2][c:3]1[cH:4][c:5]2[c:6]([O:15][c:16]3[cH:17][c:18]([NH:19][C:32]([NH:31][c:29]4[n:28](-[c:41]5[cH:42][n:43][cH:44][cH:45][cH:46]5)[n:27][c:26]([CH:23]([CH3:24])[CH3:25])[cH:30]4)=[O:33])[cH:20][cH:21][cH:22]3)[n:7][cH:8][n:9][c:10]2[cH:11][c:12]1[O:13][CH3:14]