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Tetrahydrofuran → Tert-butyl 4-(1-hydroxy-2-methylpropan-2-yl)piperazine-1-carboxylate

HRID 813801
Notes
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Reaction equation

HRID 813801 reaction equation
[Al+3:2].[C:7]([CH3:8])([CH3:9])([CH3:10])[O:11][C:12](=[O:13])[N:14]1[CH2:15][CH2:16][N:17]([C:20]([CH3:21])([CH3:22])[C:23](=[O:24])[O:25][CH2:26][CH3:27])[CH2:18][CH2:19]1.[H-:1].[H-:4].[H-:5].[H-:6].[Li+:3].[O:28]1[CH2:29][CH2:30][CH2:31][CH2:32]1>>[C:7]([CH3:8])([CH3:9])([CH3:10])[O:11][C:12](=[O:13])[N:14]1[CH2:15][CH2:16][N:17]([C:20]([CH3:21])([CH3:22])[CH2:23][OH:24])[CH2:18][CH2:19]1
ParticipantsSources & evidenceReaction notes

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 104727Aluminum CationHCID 166653Hydride4×HCID 57420344HCID 57420344, compound

Product 1

HCID 57420345Tert-butyl 4-(1-hydroxy-2-methylpropan-2-yl)piperazine-1-carboxylate

Sources & evidence

ORD record
ord-8977681e5f30401ebfe19f213d71766e
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D
DOI
10.1039/C8SC04228D

Reaction notes

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On this pageParticipantsSources & evidenceReaction notes