Tetrahydrofuran → 2-(2-Morpholin-4-ylethylamino)-4-(1,2,4,5-tetrahydro-3-benzazepin-3-yl)-6-(2,2,2-trifluoroethoxy)pyrimidine-5-carbonitrile

HRID 814026

Reaction equation

HRID 814026 reaction equation
[O:1]([CH2:2][CH2:3][CH2:4][O:5][c:12]1[n:13][c:14]([O:31][CH2:32][C:33]([F:34])([F:35])[F:36])[c:15]([C:29]#[N:30])[c:16]([N:18]2[CH2:19][CH2:20][c:21]3[c:22]([cH:25][cH:26][cH:27][cH:28]3)[CH2:23][CH2:24]2)[n:17]1)[c:6]1[cH:7][cH:8][cH:9][cH:10][cH:11]1.[O:37]1[CH2:38][CH2:39][N:40]([CH2:43][CH2:44][NH2:45])[CH2:41][CH2:42]1.[O:46]1[CH2:47][CH2:48][CH2:49][CH2:50]1>>[c:12]1([NH:45][CH2:44][CH2:43][N:40]2[CH2:39][CH2:38][O:37][CH2:42][CH2:41]2)[n:13][c:14]([O:31][CH2:32][C:33]([F:34])([F:35])[F:36])[c:15]([C:29]#[N:30])[c:16]([N:18]2[CH2:19][CH2:20][c:21]3[c:22]([cH:25][cH:26][cH:27][cH:28]3)[CH2:23][CH2:24]2)[n:17]1

Participants

4

Reactant 3

HCID 8028TetrahydrofuranHCID 4082852-MorpholinoethylamineHCID 220038782-(3-Phenoxypropoxy)-4-(1,2,4,5-tetrahydro-3-benzazepin-3-yl)-6-(2,2,2-trifluoroethoxy)pyrimidine-5-carbonitrile

Product 1

HCID 98262602-(2-Morpholin-4-ylethylamino)-4-(1,2,4,5-tetrahydro-3-benzazepin-3-yl)-6-(2,2,2-trifluoroethoxy)pyrimidine-5-carbonitrile

Sources & evidence

ORD record
ord-957da720f8a34bb2b1de0894129ce581
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Linked notes

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