Theobromine → [3-(3,7-Dimethylxanthin-1-yl)propyl]dimethylphosphine Oxide

Reaction equation

[CH3:23][CH2:24][O:25][C:26](=[O:27])[CH3:28].[CH3:2][n:3]1[c:4](=[O:14])[nH:5][c:6](=[O:13])[c:7]2[n:8]([CH3:12])[cH:9][n:10][c:11]12.[Cl:15][CH2:16][CH2:17][CH2:18][P:19]([CH3:20])([CH3:21])=[O:22].[Na:1]>>[CH3:2][n:3]1[c:4](=[O:14])[n:5]([CH2:16][CH2:17][CH2:18][P:19]([CH3:20])([CH3:21])=[O:22])[c:6](=[O:13])[c:7]2[n:8]([CH3:12])[cH:9][n:10][c:11]12