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4-Toluenesulfonyl chloride → Toluene-4-sulfonic acid 2-{1-[2-(4-cyanophenoxy)ethyl]ureido}ethyl ester

HRID 814702
Notes
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Reaction equation

HRID 814702 reaction equation
[C:1](#[N:2])[c:3]1[cH:4][cH:5][c:6]([O:7][CH2:8][CH2:9][N:10]([C:11](=[O:12])[NH2:13])[CH2:14][CH2:15][OH:16])[cH:17][cH:18]1.[CH2:19]([Li:20])[CH2:21][CH2:22][CH3:23].[CH2:35]1[O:36][CH2:37][CH2:38][CH2:39]1.[c:24]1([CH3:34])[cH:25][cH:26][c:27]([S:30](=[O:31])(=[O:32])[Cl:33])[cH:28][cH:29]1>>[C:1](#[N:2])[c:3]1[cH:4][cH:5][c:6]([O:7][CH2:8][CH2:9][N:10]([C:11](=[O:12])[NH2:13])[CH2:14][CH2:15][O:16][S:30]([c:27]2[cH:26][cH:25][c:24]([CH3:34])[cH:29][cH:28]2)(=[O:31])=[O:32])[cH:17][cH:18]1
ParticipantsSources & evidenceReaction notes

Participants

5

Reactant 4

HCID 73974-Toluenesulfonyl chlorideHCID 8028TetrahydrofuranHCID 69067579N-[2-(4-Cyanophenoxy)ethyl]-N-(2-hydroxyethyl)ureaHCID 178418339Butyllithium

Product 1

HCID 86616242Toluene-4-sulfonic acid 2-{1-[2-(4-cyanophenoxy)ethyl]ureido}ethyl ester

Sources & evidence

ORD record
ord-e42d8c0d1cc047539c359fe915e35146
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D
DOI
10.1039/C8SC04228D

Reaction notes

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On this pageParticipantsSources & evidenceReaction notes