Dichloromethane → 2-(2-(1H-pyrazolo[3,4-b]pyridin-4-yl)thiazol-4-yl)-2-methyl propanenitrile
Reaction equation
[CH2:39]([SiH:40]([CH2:41][CH3:42])[CH2:43][CH3:44])[CH3:45].[CH3:1][C:2]([C:3]#[N:4])([CH3:5])[c:6]1[n:7][c:8](-[c:11]2[c:12]3[c:13]([n:14][cH:15][cH:16]2)[n:17]([C:20]([c:21]2[cH:22][cH:23][cH:24][cH:25][cH:26]2)([c:27]2[cH:28][cH:29][cH:30][cH:31][cH:32]2)[c:33]2[cH:34][cH:35][cH:36][cH:37][cH:38]2)[n:18][cH:19]3)[s:9][cH:10]1.[Cl:53][CH2:54][Cl:55].[F:46][C:47]([F:48])([F:49])[C:50]([OH:51])=[O:52]>>[CH3:1][C:2]([C:3]#[N:4])([CH3:5])[c:6]1[n:7][c:8](-[c:11]2[c:12]3[c:13]([n:14][cH:15][cH:16]2)[nH:17][n:18][cH:19]3)[s:9][cH:10]1Participants
5
