Tetrahydrofuran → 2-(Hydroxymethyl)thiophene-3-sulfonamide

HRID 822635

Reaction equation

[BH4-:14].[Li+:15].[NH2:1][S:2](=[O:3])(=[O:4])[c:5]1[c:6]([C:10](=[O:11])[O:12][CH3:13])[s:7][cH:8][cH:9]1.[O:16]1[CH2:17][CH2:18][CH2:19][CH2:20]1>>[NH2:1][S:2](=[O:3])(=[O:4])[c:5]1[c:6]([CH2:10][OH:11])[s:7][cH:8][cH:9]1

Participants

Reactant 4

HCID 8028Tetrahydrofuran

HCID 28123Borohydride

HCID 28486Lithium ion

HCID 101012Methyl 3-(aminosulfonyl)-2-thiophenecarboxylate

Product 1

HCID 142549372-(Hydroxymethyl)thiophene-3-sulfonamide

Sources & evidence

ORD record: ord-eb84628db3034ab8b051ac54e7522dbc
Source dataset: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Linked notes

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