Dichloromethane → 1-Acetyl-4-(2-chloroethyl)piperazine

HRID 824600

Reaction equation

HRID 824600 reaction equation
[C:1]([CH3:2])(=[O:3])[N:4]1[CH2:5][CH2:6][N:7]([CH2:10][CH2:11][OH:12])[CH2:8][CH2:9]1.[CH2:31]([Cl:32])[Cl:33].[CH3:13][CH2:14][N:15]([CH2:16][CH3:17])[CH2:18][CH3:19].[c:20]1([CH3:21])[cH:22][cH:23][c:24]([S:25](=[O:26])(=[O:27])[Cl:29])[cH:28][cH:30]1>>[C:1]([CH3:2])(=[O:3])[N:4]1[CH2:5][CH2:6][N:7]([CH2:10][CH2:11][Cl:29])[CH2:8][CH2:9]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 73974-Toluenesulfonyl chlorideHCID 8471TriethylamineHCID 47396291-Acetyl-4-(2-hydroxyethyl)piperazine

Product 1

HCID 132894881-Acetyl-4-(2-chloroethyl)piperazine

Sources & evidence

ORD record
ord-3d5749cbdd3f4ac1813772c156619f94
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Linked notes

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