Hydrochloric Acid → 2-Amino-5-bromo-N-(2-methoxy-benzyl)-benzamide

HRID 824611

Reaction equation

HRID 824611 reaction equation
[CH3:11][Al:12]([CH3:13])[CH3:14].[CH3:15][O:16][C:17]([c:18]1[c:19]([NH2:25])[cH:20][cH:21][c:22]([Br:24])[cH:23]1)=[O:26].[CH3:1][O:2][c:3]1[c:4]([CH2:5][NH2:6])[cH:7][cH:8][cH:9][cH:10]1.[CH3:28][c:29]1[cH:30][cH:31][cH:32][cH:33][cH:34]1.[ClH:27]>>[CH3:1][O:2][c:3]1[c:4]([CH2:5][NH:6][C:17](=[O:16])[c:18]2[c:19]([NH2:25])[cH:20][cH:21][c:22]([Br:24])[cH:23]2)[cH:7][cH:8][cH:9][cH:10]1

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 1140TolueneHCID 812922-MethoxybenzylamineHCID 736224Methyl 2-amino-5-bromobenzoateHCID 16682925Trimethylaluminum

Product 1

HCID 219302782-Amino-5-bromo-N-(2-methoxy-benzyl)-benzamide

Sources & evidence

ORD record
ord-ffc8d5c9c404449f972fb707909a84cc
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Linked notes

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