Dimethylformamide → 4,7-Dichloro-6-nitroquinoline-3-carbonitrile

Reaction equation

[CH3:24][N:25]([CH3:26])[CH:27]=[O:28].[Cl:18][C:19]([C:20]([Cl:21])=[O:22])=[O:23].[Cl:1][c:2]1[c:3]([N+:15](=[O:16])[O-:17])[cH:4][c:5]2[c:6](=[O:14])[c:7]([C:12]#[N:13])[cH:8][nH:9][c:10]2[cH:11]1>>[Cl:1][c:2]1[c:3]([N+:15](=[O:16])[O-:17])[cH:4][c:5]2[c:6]([Cl:18])[c:7]([C:12]#[N:13])[cH:8][n:9][c:10]2[cH:11]1

Participants

Reactant 3

HCID 6228Dimethylformamide

HCID 65578Oxalyl chloride

HCID 219564857-Chloro-4-hydroxy-6-nitro-3-quinolinecarbonitrile

Product 1

HCID 219564524,7-Dichloro-6-nitroquinoline-3-carbonitrile

Sources & evidence

ORD record: ord-b1725563de4348338cf7495077360a39
Source dataset: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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