Tetrahydrofuran → HCID 59548448, compound

HRID 826937

Reaction equation

HRID 826937 reaction equation
[CH2:45]1[O:46][CH2:47][CH2:48][CH2:49]1.[CH3:20][Si:21]([N-:22][Si:23]([CH3:24])([CH3:25])[CH3:26])([CH3:27])[CH3:28].[F:30][c:31]1[n:32][cH:33][cH:34][cH:35][c:36]1-[c:37]1[n:38][c:39]([NH2:44])[n:40][c:41]([CH3:43])[n:42]1.[Li+:29].[NH2:1][c:2]1[cH:3][c:4]([NH:9][S:10](=[O:11])(=[O:12])[c:13]2[cH:14][cH:15][c:16]([F:19])[cH:17][cH:18]2)[c:5]([Cl:8])[n:6][cH:7]1>>[NH:1]([c:2]1[cH:3][c:4]([NH:9][S:10](=[O:11])(=[O:12])[c:13]2[cH:14][cH:15][c:16]([F:19])[cH:17][cH:18]2)[c:5]([Cl:8])[n:6][cH:7]1)[c:31]1[n:32][cH:33][cH:34][cH:35][c:36]1-[c:37]1[n:38][c:39]([NH2:44])[n:40][c:41]([CH3:43])[n:42]1

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 3280088Npc316347HCID 665998524-(2-Fluoropyridin-3-yl)-6-methyl-1,3,5-triazin-2-amineHCID 71480919N-(5-amino-2-chloropyridin-3-yl)-4-fluorobenzenesulfonamide

Product 1

HCID 59548448HCID 59548448, compound

Sources & evidence

ORD record
ord-a0f9d31ceec443e6a8d2d33e5789598f
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Linked notes

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