Hydrochloric Acid → Ethyl 2-chloro-4-methyl-1,3-thiazole-5-carboxylate

HRID 835777

Reaction equation

HRID 835777 reaction equation
[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[c:7]([CH3:12])[n:8][c:9]([NH2:11])[s:10]1.[CH2:21]([Cl:22])[Cl:23].[CH3:24][C:25]#[N:26].[Cl:27][Cu:28][Cl:29].[ClH:20].[N:13]([O:14][C:15]([CH3:16])([CH3:17])[CH3:18])=[O:19]>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[c:7]([CH3:12])[n:8][c:9]([Cl:22])[s:10]1

Participants

7

Reactant 6

HCID 313Hydrochloric AcidHCID 6342AcetonitrileHCID 6344DichloromethaneHCID 10906Tert-Butyl nitriteHCID 24014Cupric ChlorideHCID 343747Ethyl 2-amino-4-methylthiazole-5-carboxylate

Product 1

HCID 594903Ethyl 2-chloro-4-methyl-1,3-thiazole-5-carboxylate

Sources & evidence

ORD record
ord-490288ffb64a44adbff0180b1e92b83f
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Linked notes

Loading…