Hydrogen Bromide → 2-Bromo-1-[5-(4-bromo-phenyl)-3-methyl-isoxazol-4-yl]ethanone

Reaction equation

[Br:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[c:9]([C:14](=[O:15])[Cl:16])[c:10]([CH3:13])[n:11][o:12]2)[cH:6][cH:7]1.[BrH:24].[CH3:17][Si:18]([CH:19]=[N+:20]=[N-:21])([CH3:22])[CH3:23]>>[Br:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[c:9]([C:14](=[O:15])[CH2:17][Br:24])[c:10]([CH3:13])[n:11][o:12]2)[cH:6][cH:7]1

Participants

Reactant 3

HCID 260Hydrogen Bromide

HCID 167693Trimethylsilyldiazomethane

HCID 866524055-(4-Bromo-phenyl)-3-methyl-isoxazole-4-carbonyl chloride

Product 1

HCID 866524062-Bromo-1-[5-(4-bromo-phenyl)-3-methyl-isoxazol-4-yl]ethanone

Sources & evidence

ORD record: ord-bda6a1d9a3044dd58be54b451ea4d362
Source dataset: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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