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Hydrochloric Acid → 2-O-methyl 1-O-[(4-nitrophenyl)methyl] 4-hydroxypyrrolidine-1,2-dicarboxylate

HRID 836693
Notes
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Reaction equation

HRID 836693 reaction equation
[CH3:12][CH2:13][N:14]([CH2:15][CH3:16])[CH2:17][CH3:18].[CH3:19][c:20]1[cH:21][c:22]([CH3:23])[n:24][c:25]([S:26][C:28](=[O:29])[O:30][CH2:31][c:32]2[cH:33][cH:34][c:35]([N+:38](=[O:39])[O-:40])[cH:36][cH:37]2)[n:27]1.[CH3:2][O:3][C:4]([CH:5]1[NH:6][CH2:7][CH:8]([OH:10])[CH2:9]1)=[O:11].[CH:41]([Cl:42])([Cl:43])[Cl:44].[ClH:1]>>[CH3:2][O:3][C:4]([CH:5]1[N:6]([C:28](=[O:29])[O:30][CH2:31][c:32]2[cH:33][cH:34][c:35]([N+:38](=[O:39])[O-:40])[cH:36][cH:37]2)[CH2:7][CH:8]([OH:10])[CH2:9]1)=[O:11]
ParticipantsSources & evidenceReaction notes

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 6212ChloroformHCID 8471TriethylamineHCID 549381Methyl 4-hydroxypyrrolidine-2-carboxylateHCID 135043164,6-Dimethyl-2-(4-nitrobenzyloxycarbonylthio)pyrimidine

Product 1

HCID 135761962-O-methyl 1-O-[(4-nitrophenyl)methyl] 4-hydroxypyrrolidine-1,2-dicarboxylate

Sources & evidence

ORD record
ord-5a8f3524024140679df02588aa1cef57
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D
DOI
10.1039/C8SC04228D

Reaction notes

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On this pageParticipantsSources & evidenceReaction notes