Tetrahydrofuran → N-(5-methoxypyridin-3-yl)-3-(2-methyl-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-yl)pyridin-2-amine
Reaction equation
[CH2:43]1[O:44][CH2:45][CH2:46][CH2:47]1.[CH3:24][O:25][c:26]1[cH:27][c:28]([NH2:32])[cH:29][n:30][cH:31]1.[CH3:33][Si:34]([NH:35][Si:36]([CH3:37])([CH3:38])[CH3:39])([CH3:40])[CH3:41].[F:1][c:2]1[n:3][cH:4][cH:5][cH:6][c:7]1-[c:8]1[c:9]2[n:10][cH:11][n:12]([CH:18]3[O:19][CH2:20][CH2:21][CH2:22][CH2:23]3)[c:13]2[n:14][c:15]([CH3:17])[n:16]1.[Li:42]>>[c:2]1([NH:32][c:28]2[cH:27][c:26]([O:25][CH3:24])[cH:31][n:30][cH:29]2)[n:3][cH:4][cH:5][cH:6][c:7]1-[c:8]1[c:9]2[n:10][cH:11][n:12]([CH:18]3[O:19][CH2:20][CH2:21][CH2:22][CH2:23]3)[c:13]2[n:14][c:15]([CH3:17])[n:16]1
