Tetrahydrofuran → 3-[3,4-dimethyl-5-(2-methyl-2H-[1,2,4]triazol-3-yl)-thiophen-2-yl]-8-(1-ethyl-propyl)-2,6-dimethyl-imidazo[1,2-b]pyridazine
Reaction equation
[Br:17][c:18]1[c:19]([CH3:40])[c:20]([CH3:39])[c:21](-[c:23]2[c:24]([CH3:38])[n:25][c:26]3[n:27]2[n:28][c:29]([CH3:37])[cH:30][c:31]3[CH:32]([CH2:33][CH3:34])[CH2:35][CH3:36])[s:22]1.[CH2:7]1[O:8][CH2:9][CH2:10][CH2:11]1.[CH3:12][CH2:13][CH2:14][CH2:15][Li:16].[CH3:1][n:2]1[n:3][cH:4][n:5][cH:6]1.[CH3:41][CH2:42][O:43][C:44]([CH3:45])=[O:46]>>[CH3:1][n:2]1[n:3][cH:4][n:5][c:6]1-[c:18]1[c:19]([CH3:40])[c:20]([CH3:39])[c:21](-[c:23]2[c:24]([CH3:38])[n:25][c:26]3[n:27]2[n:28][c:29]([CH3:37])[cH:30][c:31]3[CH:32]([CH2:33][CH3:34])[CH2:35][CH3:36])[s:22]1
