p-Toluenesulfonic acid → N'-(propan-2-ylidene)benzenesulfonohydrazide

HRID 844404

Reaction equation

HRID 844404 reaction equation
[C:1]1([S:7]([NH:10][NH2:11])(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:12]1(C)[CH:17]=CC(S(O)(=O)=O)=C[CH:13]=1>CC(C)=O>[CH3:13][C:12](=[N:11][NH:10][S:7]([C:1]1[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1)(=[O:8])=[O:9])[CH3:17]

Participants

4

Reactant 2

HCID 6101p-Toluenesulfonic acidHCID 65723Benzenesulfonyl hydrazide

Product 1

HCID 280407N'-(propan-2-ylidene)benzenesulfonohydrazide

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Conditions

Temperature
20 °C

Procedure

A four neck flask (1 liter) equipped with a thermometer, a reflux condenser and a stirrer was charged with 86 g (0.5 mol) of benzenesulfonohydrazide, 0.95 g (0.005 mol) of p-toluenesulfonic acid and 700 ml of acetone and then heated under reflux for about 5 hours. The reaction liquid was cooled down to 20° C. or lower, and then crystal was filtered off and dried under reduced pressure, whereby white crystal was obtained.

Workup

  1. customA four neck flask (1 liter) equipped with a thermometer, a reflux condenser and a stirrer
  2. temperatureheated
  3. temperatureunder reflux for about 5 hours
  4. customThe reaction liquid
  5. filtrationlower, and then crystal was filtered off
  6. customdried under reduced pressure, whereby white crystal
  7. customwas obtained

Sources & evidence

ORD record
ord-d9380f4f7013413cba21ca57c694bfbf
Source dataset
uspto-grants-2002_04
Patent number
US06380288B1

Linked notes

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