Methanol → 2-Benzyl-6-(4-methoxyphenyl)-1,3,4,4a,5,7,8,8a-octahydroisoquinolin-6-ol

HRID 85948

Reaction equation

HRID 85948 reaction equation
[Al+3:29].[C:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)(=[O:8])[N:9]1[CH2:10][CH:11]2[CH2:12][CH2:13][C:14]([c:19]3[cH:20][cH:21][c:22]([O:25][CH3:26])[cH:23][cH:24]3)([OH:27])[CH2:15][CH:16]2[CH2:17][CH2:18]1.[CH2:40]1[O:41][CH2:42][CH2:43][CH2:44]1.[CH3:38][OH:39].[CH:34]([Cl:35])([Cl:36])[Cl:37].[H-:28].[H-:31].[H-:32].[H-:33].[Li+:30]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:9]1[CH2:10][CH:11]2[CH2:12][CH2:13][C:14]([c:19]3[cH:20][cH:21][c:22]([O:25][CH3:26])[cH:23][cH:24]3)([OH:27])[CH2:15][CH:16]2[CH2:17][CH2:18]1

Participants

8

Reactant 7

HCID 887MethanolHCID 6212ChloroformHCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 104727Aluminum CationHCID 166653Hydride4×HCID 19438913[6-Hydroxy-6-(4-methoxyphenyl)-1,3,4,4a,5,7,8,8a-octahydroisoquinolin-2-yl]-phenylmethanone

Product 1

HCID 194389262-Benzyl-6-(4-methoxyphenyl)-1,3,4,4a,5,7,8,8a-octahydroisoquinolin-6-ol

Sources & evidence

ORD record
ord-7ce0d057a237453a94bbfb83f51759c4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

Loading…