Triethylamine → (2-(4-Fluoro-phenylethynyl)-6-methyl-pyridin-3-yl)amine

HRID 85958

Reaction equation

HRID 85958 reaction equation
[Br:1][c:2]1[n:3][c:4]([CH3:9])[cH:5][cH:6][c:7]1[NH2:8].[C:10](#[CH:11])[c:12]1[cH:13][cH:14][c:15]([F:18])[cH:16][cH:17]1.[CH3:19][CH2:20][N:21]([CH2:22][CH3:23])[CH2:24][CH3:25].[Pd:26]([Cl:27])[Cl:28].[c:29]1([P:30]([c:31]2[cH:32][cH:33][cH:34][cH:35][cH:36]2)[c:37]2[cH:38][cH:39][cH:40][cH:41][cH:42]2)[cH:43][cH:44][cH:45][cH:46][cH:47]1.[c:48]1([P:49]([c:50]2[cH:51][cH:52][cH:53][cH:54][cH:55]2)[c:56]2[cH:57][cH:58][cH:59][cH:60][cH:61]2)[cH:62][cH:63][cH:64][cH:65][cH:66]1>>[c:2]1([C:11]#[C:10][c:12]2[cH:13][cH:14][c:15]([F:18])[cH:16][cH:17]2)[n:3][c:4]([CH3:9])[cH:5][cH:6][c:7]1[NH2:8]

Participants

6

Reactant 5

HCID 8471TriethylamineHCID 11776Triphenylphosphine2×HCID 24290Palladium ChlorideHCID 5226271-Ethynyl-4-fluorobenzeneHCID 144180512-Bromo-6-methylpyridin-3-amine

Product 1

HCID 10105101(2-(4-Fluoro-phenylethynyl)-6-methyl-pyridin-3-yl)amine

Sources & evidence

ORD record
ord-7c33790cde2e4491aeca7672dcc473e9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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