Water → 2-(4-(2,2-Diethoxyethoxy)-2,3-difluorophenyl)ethanol

Reaction equation

[Br:19][CH2:20][CH:21]([O:22][CH2:23][CH3:24])[O:25][CH2:26][CH3:27].[C:1](=[O:2])([O-:3])[O-:4].[Cs+:5].[Cs+:6].[F:7][c:8]1[c:9]([OH:18])[cH:10][cH:11][c:12]([CH2:15][CH2:16][OH:17])[c:13]1[F:14].[O:29]=[CH:30][N:31]([CH3:32])[CH3:33].[OH2:28]>>[F:7][c:8]1[c:9]([O:18][CH2:20][CH:21]([O:22][CH2:23][CH3:24])[O:25][CH2:26][CH3:27])[cH:10][cH:11][c:12]([CH2:15][CH2:16][OH:17])[c:13]1[F:14]

Participants

Reactant 6

HCID 962Water

HCID 6228Dimethylformamide

HCID 19660Carbonate Ion

HCID 74852Ethane, 2-bromo-1,1-diethoxy-

HCID 104967Cesium cation2×

HCID 534161452,3-Difluoro-4-(2-hydroxyethyl)phenol

Product 1

HCID 579889892-(4-(2,2-Diethoxyethoxy)-2,3-difluorophenyl)ethanol

Sources & evidence

ORD record: ord-1cbe7a0fe5714d9e867ba827a3961d40
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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