Dimethylformamide → 2-Chloro-4-(2-furyl)thieno[3,2-d]pyrimidine

HRID 87155

Reaction equation

HRID 87155 reaction equation
[CH2:12]([Sn:13]([CH2:14][CH2:15][CH2:16][CH3:22])([c:17]1[o:18][cH:19][cH:20][cH:21]1)[CH2:23][CH2:24][CH2:25][CH3:26])[CH2:27][CH2:28][CH3:29].[Cl:1][c:2]1[n:3][c:4]([Cl:11])[c:5]2[c:6]([n:7]1)[cH:8][cH:9][s:10]2.[O:30]=[CH:31][N:32]([CH3:33])[CH3:34].[Pd:35]([Cl:36])[Cl:37].[c:38]1([P:39]([c:40]2[cH:41][cH:42][cH:43][cH:44][cH:45]2)[c:46]2[cH:47][cH:48][cH:49][cH:50][cH:51]2)[cH:52][cH:53][cH:54][cH:55][cH:56]1.[c:57]1([P:58]([c:59]2[cH:60][cH:61][cH:62][cH:63][cH:64]2)[c:65]2[cH:66][cH:67][cH:68][cH:69][cH:70]2)[cH:71][cH:72][cH:73][cH:74][cH:75]1>>[Cl:1][c:2]1[n:3][c:4](-[c:17]2[o:18][cH:19][cH:20][cH:21]2)[c:5]2[c:6]([n:7]1)[cH:8][cH:9][s:10]2

Participants

6

Reactant 5

HCID 6228DimethylformamideHCID 11776Triphenylphosphine2×HCID 24290Palladium ChlorideHCID 43936882-(Tributylstannyl)furanHCID 127128322,4-Dichlorothieno[3,2-d]pyrimidine

Product 1

HCID 597323872-Chloro-4-(2-furyl)thieno[3,2-d]pyrimidine

Sources & evidence

ORD record
ord-fa32fa93069445bdb5bfbb56c1fbefd4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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